Vertical Autoclave NVA-401 is a very high-capacity laboratory steam sterilizer that uses pressurized steam at 121–136°C to sterilize instruments, glassware, liquids, and biohazardous waste. It is designed for large laboratories, hospitals, and pharmaceutical facilities requiring high-throughput, compliant sterilization.
Sterilization Type: Steam (121–136°C)
Capacity: 250–450 L
Pressure: 1.0–2.6 bar
Cycle Types: Gravity & Pre-vacuum
Best For: Large labs, pharma, high-throughput use
Vertical Autoclave NVA-401 is designed for very high-capacity sterilization in laboratory, clinical, and pharmaceutical environments. It ensures elimination of microorganisms and supports compliance with USP, ISO 17665, and GMP standards.
Sterilizing large volumes of instruments and glassware
Decontaminating biohazardous waste
Preparing bulk sterile culture media
Supporting pharmaceutical production workflows
Load materials into chamber
Add water and secure lid
Select sterilization cycle
Heat to 121–136°C
Maintain pressure for required time
Allow cooling before unloading
Autoclave uses pressurized steam to destroy microorganisms and spores. Air is removed through gravity displacement or pre-vacuum cycles to ensure deep steam penetration.
Very high-capacity chamber (250–450 L)
Steam sterilization at 121–136°C
Gravity and pre-vacuum cycles
Programmable sterilization cycles
Digital monitoring system
Safety interlocks and alarms
Choose this model if you need:
Very high-capacity sterilization
Bulk or continuous batch processing
Liquid + solid load sterilization
GMP/ISO-compliant production environments
Autoclaves operate at 121°C or up to 134–136°C to effectively eliminate microorganisms and spores.
Autoclave pressure typically ranges from 1.0 to 2.6 bar depending on cycle requirements.
A typical cycle takes 15 to 60 minutes depending on load size and sterilization settings.
121°C is effective for destroying heat-resistant bacteria and spores while maintaining material safety.
Yes, autoclaves destroy bacteria, viruses, fungi, and spores when operated correctly.
Yes, liquids can be sterilized using controlled cycles to prevent boiling and ensure uniform sterilization.
Yes, modern autoclaves include safety systems like pressure valves, door locks, and alarms.
Pharmaceutical manufacturing
Biotechnology laboratories
Hospitals and clinical labs
Research institutions
Food testing laboratories
High-volume instrument sterilization
Bulk culture media preparation
Biohazard waste treatment
Pharmaceutical sterilization processes
USP guidelines
ISO 17665
GMP compliance
Vertical Autoclave NVA-401 is a very high-capacity steam sterilizer designed for large-scale laboratory and pharmaceutical applications. With programmable cycles, safety features, and regulatory compliance, it ensures accurate and repeatable sterilization for high-throughput environments.
