Transmagnetite is a novel, simple and highly efficient method to transfect cells in culture. It exploits magnetic force exerted upon gene vectors associated with magnetic particles to draw the vectors towards, possibly even into, the target cells. In this manner, the full vector dose applied gets concentrated on the cells within a few minutes so that 100% of the cells get in contact with a significant vector dose. This has many advantages:

Greatly improved transfection rates in terms of percentage of cells transfected compared to standard transfection.

Up to several thousand fold increased levels of transgene expression compared to standard transfections upon short-term incubation.

High transfection rates and transgene expression levels are achievable with extremely low vector doses, which allows to save expensive transfection reagents.

Extremely short process time. A few minutes of incubation of cells with gene vectors are sufficient to generate high transfection efficiency, compared to several hours with standard procedures.